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Public Profile -- hu6D1115

Public profile url: https://my-dev.pgp-hms.org/profile/hu6D1115

Personal Health Records

Demographic Information

Date of Birth1944-06-01 (81 years old)
GenderFemale
Weight119lbs (54kg)
Height5ft 4in (162cm)
Blood TypeA+
RaceWhite

Conditions

Name Start Date End Date
Age Spots
Airplane ear
Allergic Drug Reaction
Anemia, folate-deficiency
Astigmatism
Birthmarks
Bronchitis 1949-01-01 1950-01-01
Bruises
Canker sores
Cavities
Cervical Dysplasia 1990-01-01
Chickenpox 1953-01-01
Child abuse, physical 1946-01-01 1963-01-01
Cigarette Smoker 1964-01-01 1973-01-01
Cocaine intoxication 1972-01-01 1972-01-01
Common cold
Cough
Cyst 1977-01-01 1979-01-01
Dandruff
Decreased visual acuity 1989-01-01
Dental Caries
Dental cavities
Diarrhea
Dizziness
Dry Skin
Ear Wax Impaction 2004-01-01
Excessive gas
Eyelid Twitch
Fingernail Injury
Flatulence
Flea Bites
Folate-deficiency anemia
Folic acid deficiency
Fructose Intolerance
Gingivitis
Gum Disease 1997-01-01
Hay fever
Hiccups
High blood triglycerides
High Cholesterol
Homocystinuria
Hypothyroidism 1990-01-01
Ice cream headaches
Impacted wisdom teeth
Influenza
Insect Bites
Insect bites and stings
Iron Deficiency Anemia 2009-01-01
Itching
Laryngitis
Leg Cramps
Marijuana intoxication 1970-01-01 1980-01-01
Menopause 1989-01-01
Menstrual Periods, Absent
Metabolic syndrome 1990-01-01 2003-02-01
Moles
Motion Sickness
Neck Stiffness
Night Terrors
Nightmares
Nosebleed
Ovarian cysts 1989-01-01
Painful Urination
Periodontal Disease
Pimples
Pink eye
Plantar warts
Poison Oak
Psoriasis
Rotator Cuff Injury
Rotator Cuff Strain
Rotator Cuff Tendinitis
Scabies 2004-02-01
Shoulder Pain
Shoulder Strain
Shoulder Tendinitis
Skin Photosensitivity
Skin Rash 2009-01-01
Skin tags
Sore Throat
Stomach Cramps
Stomach flu
Stress Incontinence
Sunburn
Teeth Grinding
Toenail Injury
Tonsillitis
Tooth Decay
Toxic Shock Syndrome 1985-01-01
Traveler's Diarrhea
Underactive Thyroid
Unintentional weight gain
Urinary Tract Infection (UTI)
Vaginal yeast infection
Viral Pneumonia 1949-01-01 1950-01-01
Vomiting
Warts, plantar
Whiteheads
Wrinkles
Wrist pain
Yeast infection, vaginal
Zits

Medications

Name Dosage Frequency Start Date End Date
Alpha-Lipoic Acid
Calcium Magnesium Vitamins D & K
Calcium-Vitamin D3-Vitamin K
Co Q-10
Curcumoids-Tumeric
DHEA
Ferrochel
Fluocinonide-Cream To skin
Folgard RX
latisse
Levothyroxine
Pravastatin
Pregnenolone
Probiotic -Sacchro
Resveratin

Allergies

Name Reaction/Severity Start Date End Date
Sulfa (Sulfonamides) Severe

Procedures

Name Date
Abdominoplasty
Eyelid Lift
Facelift
Forehead Lift
Liposuction - Head and Neck
Liposuction - Trunk
salpingoophrectomy
Tonsillectomy - With Adenoidectomy

Test Results

Name Result Date
Lipoprotein-a (Lp(a)) 24 mG/dl 1998-09-15
HDL Cholesterol 47 mG/dl 1998-09-15
LDL Cholesterol 116 mG/dl 1998-09-15
Homocysteine - Serum 47.7 umoL/L 1998-09-15
Cholesterol, Total 201 mG/dl 1998-09-15
Triglycerides, Blood 192 mG/dl 1998-09-15
Albumin, Serum 4.6 2009-02-28
Weight 2016 ounces 2009-09-12
Height 64 inches 2009-09-12
C-reactive Protein (CRP) <0.10 2010-02-03
Taurine 76 umo/L 2010-06-21
Methylmalonic Acid Test 139 nmol/L 2010-06-21
Phosphoethanolamine 11 umo/L 2010-06-21
Homocysteine - Serum 9 umoL/L 2010-06-21
Creatinine, Serum 0.8 mg/dL 2010-07-13
Sodium, Blood 142 mEq/L 2010-07-13
Total Protein 7.2 g/dL 2010-07-13
Triglycerides, Blood 113 mG/dl 2010-07-13
Globulin - Serum 2.5 g/dL 2010-07-13
ALT/SGPT 18 u/L 2010-07-13
BUN 12 mg/dL 2010-07-13
Creatine Phosphokinase (CPK) 128 u/L 2010-07-13
Alkaline Phosphatase 77 IU/L 2010-07-13
TSH Receptor Antibody 1.701 ulU/mL 2010-07-13
AST/SGOT 20 u/L 2010-07-13
Glomerular Filtration Rate (GFR), Predicted >60.0 2010-07-13
Potassium, Serum 3.9 mEq/L 2010-07-13
Bicarbonate - Serum 25 mEq/L 2010-07-13
Very Low Density Lipoprotein (VLDL) Cholesterol 22.6 2010-07-13
Albumin, Serum 4.7 2010-07-13
Cholesterol, Total 178 mG/dl 2010-07-13
Bilirubin, Direct 0.10 mg/dL 2010-07-13
Chloride, Serum 103 mEq/L 2010-07-13
Bilirubin, Indirect 0.2 mg/dL 2010-07-13
Calcium, Serum 10.0 mg/dL 2010-07-13
Thyroxine (T4), Free - Serum 1.08 ng/dL 2010-07-13
HDL Cholesterol 64 mG/dl 2010-07-13
Bilirubin, Total 0.3 mg/dL 2010-07-13
LDL Cholesterol 91 mG/dl 2010-07-13
Glucose, Fasting - Plasma 74 mg/DL 2010-09-02
Hemoglobin A1c (HbA1c) 5.1 % 2010-09-02
Weight 123 lb 2010-10-10
Weight 122 lb 2010-10-13
Cholesterol, Total 156 mG/dl 2010-11-03
Very Low Density Lipoprotein (VLDL) Cholesterol 15.2 2010-11-03
Bilirubin, Total 0.4 mg/dL 2010-11-03
Alkaline Phosphatase 72 IU/L 2010-11-03
Bilirubin, Indirect 0.3 mg/dL 2010-11-03
Homocysteine - Serum 14.3 umoL/L 2010-11-03
ALT/SGPT 18 u/L 2010-11-03
Globulin - Serum 2.2 g/dL 2010-11-03
Albumin, Serum 4.4 2010-11-03
Bilirubin, Direct 0.10 mg/dL 2010-11-03
LDL Cholesterol 77 mG/dl 2010-11-03
AST/SGOT 19 u/L 2010-11-03
Total Protein 6.6 g/dL 2010-11-03
HDL Cholesterol 64 mG/dl 2010-11-03
Creatine Phosphokinase (CPK) 101 u/L 2010-11-03
Triglycerides, Blood 76 mG/dl 2010-11-03
Weight 122 lb 2010-11-12
Weight 123 lb 2010-11-18
Weight 122 lb 2010-12-18
Weight 121 lb 2010-12-30
BUN 12.8 mg/dL 2011-01-25
Apolipoprotein A 179 mg/dL 2011-01-25
Sodium, Blood 142 mEq/L 2011-01-25
Apolipoprotein B100 (ApoB100) 82 mg/dL 2011-01-25
Triglycerides, Blood 75 mG/dl 2011-01-25
LDL Cholesterol 78 mG/dl 2011-01-25
Total Protein 6.8 g/dL 2011-01-25
Potassium, Serum 4.9 mEq/L 2011-01-25
Cholesterol, Total 176 mG/dl 2011-01-25
Homocysteine - Serum 9.5 umoL/L 2011-01-25
Chloride, Serum 106 mEq/L 2011-01-25
Glucose, Fasting - Plasma 76 mg/DL 2011-01-25
Carbon Dioxide - Serum 28 mmol/l 2011-01-25
Calcium, Serum 9.9 mg/dL 2011-01-25
Very Low Density Lipoprotein (VLDL) Cholesterol 16 2011-01-25
C-reactive Protein (CRP) 0.5 2011-01-25
HDL Cholesterol 66 mG/dl 2011-01-25
Creatinine, Serum 0.7 mg/dL 2011-01-25
Weight 122 lb 2011-02-04
LDL Cholesterol 67 mG/dl 2011-06-15
Eosinophil Count, Blood 6 2011-06-15
Eos (Absolute) 0.3 x10E/uL 2011-06-15
Triglycerides, Blood 183 mG/dl 2011-06-15
Hematocrit 36.3 2011-06-15
Hemoglobin - Blood 11.7 g/dL 2011-06-15
Creatine Phosphokinase (CPK) 97 u/L 2011-06-15
Red Blood Cell (RBC) Count 4.11 x10E6/uL 2011-06-15
Homocysteine - Serum 11.2 umoL/L 2011-06-15
Cholesterol, Total 174 mG/dl 2011-06-15
Very Low Density Lipoprotein (VLDL) Cholesterol 37 2011-06-15
Bilirubin, Total 0.4 mg/dL 2011-06-15
Bilirubin, Direct 0.12 mg/dL 2011-06-15
RDW 13.9 2011-06-15
Immature Granulocytes 0 2011-06-15
Basophils - Blood 1 2011-06-15
Baso (Absolute) 0.0 x10E3/uL 2011-06-15
Total Protein 6.6 g/dL 2011-06-15
Monocytes - Blood 6 2011-06-15
wbc 5.2 x10E3/ul 2011-06-15
Weight 124 lb 2011-06-15
HDL Cholesterol 70 mG/dl 2011-06-15
Platelet Count 323 x10E/uL 2011-06-15
Neutrophils (Absolute) 3.0 x10E3/uL 2011-06-15
ALT/SGPT 16 u/L 2011-06-15
Alkaline Phosphatase 69 IU/L 2011-06-15
Neutrophils - Blood 58 2011-06-15
Lymphs 29 2011-06-15
Lymphs (Absolute) 1.5 x10E3/uL 2011-06-15
Mean Corpuscular Hemoglobin (MCH) 28.5 pg 2011-06-15
Mean Corpuscular Hemoglobin Concentration (MCHC) 32.2 g/dL 2011-06-15
Mean Corpuscular Volume (MCV) 88 fL 2011-06-15
Albumin, Serum 4.4 2011-06-15
Monocytes (Absolute) .03 x10E3/uL 2011-06-15
AST/SGOT 20 u/L 2011-06-15
Linoleic LA 9.8 % 2011-10-10
HDL2 16 mg/dL 2011-10-11
Lp-PLA 96 ng/mL 2011-10-11
NT-proBNP 84 mg/dL 2011-10-11
Omega-3 Total 14.4 % 2011-10-11
Lipoprotein-a (Lp(a)) 13 mG/dl 2011-10-11
LDL-P 1382 nmol/L 2011-10-11
LDL Cholesterol 77 mG/dl 2011-10-11
Insulin, Serum 6 uU/mL 2011-10-11
HS-Omega-3 Index (RBC EPA + DHA) 9.4 % 2011-10-11
Homocysteine - Serum 13 umoL/L 2011-10-11
Saturated Fatty Acids Total 40.3 % 2011-10-11
sdLDL 16 mg/dL 2011-10-11
Myeloperoxidase Antibody - Serum 320 pmol/L 2011-10-11
HDL-P 34.9 umol/L 2011-10-11
HDL Cholesterol 56 mG/dl 2011-10-11
25-Hydroxy Vitamin D 50 ng/mL 2011-10-11
HbA1c 5.1 % 2011-10-11
Total Protein 6.7 g/dL 2011-10-11
Galectin-3 12.0 ng/mL 2011-10-11
Free Fatty Acid 1.44 mmol/L 2011-10-11
ALA Alpha-Linolenic 0.2 % 2011-10-11
Fibrinogen 307 mg/dL 2011-10-11
Trans Fatty Acids Total 0.5 % 2011-10-11
Triglycerides, Blood 59 mG/dl 2011-10-11
Eicosapentaenoic EPA 2.9 % 2011-10-11
Eiconsapentaenoic EPA 2.9 % 2011-10-11
Arachidonic AA 12.1 % 2011-10-11
Docosahexaenoic DHA 6.5 % 2011-10-11
CK 90 U/L 2011-10-11
Albumin, Serum 4.5 2011-10-11
cis-Monounsaturated Fatty Acids Total 18.8 % 2011-10-11
Cholesterol, Total 143 mG/dl 2011-10-11
C-Reactive Protein, High Sensitivity (hsCRP) 0.4 mg/L 2011-10-11
Bilirubin, Total 0.5 mg/dL 2011-10-11
Bilirubin, Direct 0.2 mg/dL 2011-10-11
Vitamin B12 Level 1554 pg/mL 2011-10-11
AST/SGOT 20 u/L 2011-10-11
ALP 62 U/L 2011-10-11
ALT/SGPT 15 u/L 2011-10-11
APB:APO A-1 Ratio (calculated) 0.58 2011-10-11
Apolipoprotein A 137 2011-10-11
Apolipoprotein B100 (ApoB100) 79 mg/dL 2011-10-11
DPA Docosapentaenoic 4.8 % 2011-10-11
Thyroxine (T4), Free - Serum 1.4 ng/dL 2011-11-01
TSH Receptor Antibody 0.94 ulU/mL 2011-11-01
Folate - RBC 2503 ng/mL 2011-11-24
Weight 119.5 lb 2011-11-24
Weight 118 lb 2011-12-10
Weight 118 lb 2011-12-10
Weight 118 lb 2011-12-13
Weight 119 lb 2011-12-22

Immunizations

Name Date
Chickenpox Vaccine
Diphtheria/Tetanus (DT) Toxoids, Pediatric
Flu Shot
Hepatitis A Vaccine, Pediatric/Adolescent, 3 Dose
Measles/Mumps/Rubella (MMR) Vaccine
Poliovirus vaccine, inactivated (IPV)
Poliovirus Vaccine, Live, Oral (OPV)
Shingles Vaccine
Tetanus/Diphteria (Td) Toxoids, Older Children and Adults
Typhoid Vaccine, Unknown Type

Updated: 2011-12-22T21:35:47.956Z

Samples

Saliva Collection Pilot Study for 100 participants Sample 90146765 (saliva) received 2011-12-02 20:45:29 UTC by Harvard University / TeloMe, Inc..   Show log
2012-04-12 21:02:45 UTC Harvard University / TeloMe, Inc. A new sample 93439769 was derived from this sample
2011-12-02 20:45:35 UTC Harvard University / TeloMe, Inc. Sample transferred to plate 92569876 (id=4) well B06 (id=18)
2011-12-02 20:45:29 UTC Harvard University / TeloMe, Inc. Sample received by researcher (scan)
2011-10-22 03:59:12 UTC hu6D1115 Sample returned to researcher
2011-08-11 00:44:23 UTC hu6D1115 Sample received by participant
2011-08-02 15:09:50 UTC Harvard University / TeloMe, Inc. Sample sent
2011-08-02 04:03:20 UTC Harvard University / TeloMe, Inc. Sample created
Sample 7916857 (saliva) received 2011-12-02 20:17:47 UTC by Harvard University / TeloMe, Inc..   Show log
2012-04-12 21:02:45 UTC Harvard University / TeloMe, Inc. A new sample 36629533 was derived from this sample
2011-12-02 20:17:54 UTC Harvard University / TeloMe, Inc. Sample transferred to plate 92569876 (id=4) well B05 (id=17)
2011-12-02 20:17:47 UTC Harvard University / TeloMe, Inc. Sample received by researcher (scan)
2011-10-22 03:59:12 UTC hu6D1115 Sample returned to researcher
2011-08-11 00:44:23 UTC hu6D1115 Sample received by participant
2011-08-02 15:09:50 UTC Harvard University / TeloMe, Inc. Sample sent
2011-08-02 04:03:20 UTC Harvard University / TeloMe, Inc. Sample created
Sample 28619635 (saliva) mailed 2011-10-22 03:59:12 UTC by hu6D1115.   Show log
2011-10-22 03:59:12 UTC hu6D1115 Sample returned to researcher
2011-08-11 00:44:23 UTC hu6D1115 Sample received by participant
2011-08-02 15:09:50 UTC Harvard University / TeloMe, Inc. Sample sent
2011-08-02 04:03:20 UTC Harvard University / TeloMe, Inc. Sample created
Saliva Collection for Multiple Studies Sample 64511820 (saliva) mailed 2012-02-08 02:13:44 UTC by hu6D1115.   Show log
2012-04-12 21:05:46 UTC Harvard University / TeloMe, Inc. A new sample 02371293 was derived from this sample
2012-02-08 02:13:44 UTC hu6D1115 Sample returned to researcher
2012-01-11 00:04:51 UTC Harvard University / TeloMe, Inc. Sample transferred to plate 25942764 (id=13) well D07 (id=43)
2011-12-23 16:10:04 UTC hu6D1115 Sample received by participant
2011-12-03 20:27:39 UTC Harvard University / TeloMe, Inc. Sample sent
2011-11-30 00:02:49 UTC Harvard University / TeloMe, Inc. Sample created
Sample 31273880 (saliva) mailed 2012-02-08 02:13:44 UTC by hu6D1115.   Show log
2012-04-12 21:06:06 UTC Harvard University / TeloMe, Inc. A new sample 28595092 was derived from this sample
2012-02-08 02:13:44 UTC hu6D1115 Sample returned to researcher
2012-01-11 00:33:23 UTC Harvard University / TeloMe, Inc. Sample transferred to plate 11192313 (id=14) well D07 (id=43)
2011-12-23 16:10:04 UTC hu6D1115 Sample received by participant
2011-12-03 20:27:39 UTC Harvard University / TeloMe, Inc. Sample sent
2011-11-30 00:02:49 UTC Harvard University / TeloMe, Inc. Sample created
Saliva Re-collection for Multiple Studies Sample 12655519 (saliva) received 2012-05-23 23:28:44 UTC by Harvard University / TeloMe, Inc..   Show log
2012-05-23 23:28:44 UTC Harvard University / TeloMe, Inc. Sample received by researcher
2012-04-09 05:55:00 UTC hu6D1115 Sample received by participant
2012-03-25 00:38:11 UTC Harvard University / TeloMe, Inc. Sample sent
2012-03-06 15:29:31 UTC Harvard University / TeloMe, Inc. Sample created
Sample 97209829 (saliva) received 2012-05-23 23:28:50 UTC by Harvard University / TeloMe, Inc..   Show log
2012-05-23 23:28:50 UTC Harvard University / TeloMe, Inc. Sample received by researcher
2012-04-09 05:55:00 UTC hu6D1115 Sample received by participant
2012-03-25 00:38:11 UTC Harvard University / TeloMe, Inc. Sample sent
2012-03-06 15:29:31 UTC Harvard University / TeloMe, Inc. Sample created
Sample 58604656 (saliva) received 2012-05-23 23:28:49 UTC by Harvard University / TeloMe, Inc..   Show log
2012-05-23 23:28:49 UTC Harvard University / TeloMe, Inc. Sample received by researcher
2012-04-09 05:55:00 UTC hu6D1115 Sample received by participant
2012-03-25 00:38:11 UTC Harvard University / TeloMe, Inc. Sample sent
2012-03-06 15:29:31 UTC Harvard University / TeloMe, Inc. Sample created

Uploaded data

Date Data type Source Name Download Report
2011-07-16 23andMe Participant Leslie Hoag Hope 23andme Download
(4.95 MB)

Geographic Information

State:California
Zip code:90402

Family Members Enrolled

None added.

Surveys

PGP Participant Survey Responses submitted 7/16/2011 21:47:13. Show responses
Timestamp 7/16/2011 21:47:13
Year of birth 60-69 years
Which statement best describes you? I am comfortable making my genome sequence data publicly available without prior review.
Severe disease or rare genetic trait Yes
Do you have a severe genetic disease or rare genetic trait? If so, you can add a description for your public profile. high homocysteine the answer below is when I first became aware of it as a result of my father's heart attack.
Disease/trait: Onset 40-49 years of age
Disease/trait: Rarity Uncommon
Disease/trait: Severity Not applicable
Disease/trait: Relative enrollment No
Disease/trait: Diagnosis Yes
Disease/trait: Genetic confirmation Yes
Disease/trait: Documentation Yes
Disease/trait: Documentation description Last year I was tested by a pediatric geneticist at UCLA who specializes in the condition in newborns. It was determined that I am hetrozygous for the MTHFR C677T variant. Many years prior to that my father's cardiologist reported that he had the highest homocysteine ever seen by a lab in Western Canada and recommended that he tell his offsprings to be tested for the condition. My homocysteine level was found to be quite high though it has subsequently been reduced by treatment. I have entered both my initial and my current homocysteine levels in Google Health.
Sex/Gender Female
Race/ethnicity White
Maternal grandmother: Country of origin United States
Paternal grandmother: Country of origin United States
Paternal grandfather: Country of origin United States
Maternal grandfather: Country of origin United States
Enrollment of relatives No
Enrollment of older individuals Yes
Enrollment of parents No
Have you uploaded genetic data to your PGP participant profile? No, but I have genetic data and plan to upload it
Have you used the PGP web interface to record a designated proxy? Yes
Have you uploaded health record data using our Google Health or Microsoft Healthvault interfaces? Yes
Uploaded health records: Update status Yes
Uploaded health records: Extensiveness 5
Blood sample Yes
Saliva sample Yes
Microbiome samples Yes
Tissue samples from surgery Yes
Tissue samples from autopsy Yes
PGP Participant Survey Responses submitted 10/16/2011 0:51:42. Show responses
Timestamp 10/16/2011 0:51:42
Year of birth 60-69 years
Which statement best describes you? I am comfortable making my genome sequence data publicly available without prior review.
Severe disease or rare genetic trait Yes
Do you have a severe genetic disease or rare genetic trait? If so, you can add a description for your public profile. I have high homocysteine although I control it with Folgard 2.2 rx I don't know if this condition is considered *rare* but mine is definitely genetic in origin as my father also had the condition. I suspect that my paternal grandmother and uncle also had it.
Disease/trait: Onset Congenital / present at birth
Disease/trait: Rarity Uncommon
Disease/trait: Severity Moderate severity disease
Disease/trait: Relative enrollment No
Disease/trait: Diagnosis Yes
Disease/trait: Genetic confirmation Yes
Disease/trait: Documentation Yes
Disease/trait: Documentation description I saw a pediatric geneticist at UCLA (Ronald Reagan Medical Center) who had me tested for a couple of gene variants and other factors. I have the test results as well as his narrative. However, I do believe there are also other gene variants relative to this condition that I haven't been tested for, such as MTHFD1L. I'm very curious about my risk for Alzheimer's as it relates to homocystememia. I am homozygous for APOE 3 and no one in my family has developed dementia BUT on my father's side where the homocystemia comes from, they tended to die of cardiovascular disease/stroke before late onset dementia could present.
Sex/Gender Female
Race/ethnicity White
Maternal grandmother: Country of origin United States
Paternal grandmother: Country of origin United States
Paternal grandfather: Country of origin United States
Maternal grandfather: Country of origin United States
Enrollment of relatives No
Enrollment of older individuals Yes
Enrollment of parents No
Have you uploaded genetic data to your PGP participant profile? Yes, I have uploaded genetic data
Have you used the PGP web interface to record a designated proxy? Yes
Have you uploaded health record data using our Google Health or Microsoft Healthvault interfaces? Yes
Uploaded health records: Update status Yes
Uploaded health records: Extensiveness 5
Blood sample Yes
Saliva sample Yes
Microbiome samples Yes
Tissue samples from surgery Yes
Tissue samples from autopsy Yes
PGP Participant Survey Responses submitted 11/24/2011 3:10:23. Show responses
Timestamp 11/24/2011 3:10:23
Year of birth 60-69 years
Which statement best describes you? I am comfortable making my genome sequence data publicly available without prior review.
Severe disease or rare genetic trait Yes
Do you have a severe genetic disease or rare genetic trait? If so, you can add a description for your public profile. It is not that rare, but potentially severe. I'm hetrozygous for MTHFR C677T. When I was diagnosed in 1998, my homocysteine level was 48. That is pretty high for a CT. There have to be multiple factors at work to drive my homocysteine level so high. It isn't my diet as I'm a healthy eater. What could they be? Recently I came across a study that sheds some light on my question. I found out that in combination with MTFHR 677>CT, I am a homozygous CC for SLC19A1 rs819130 which supposedly causes a 10% increase of homocysteine levels in carriers on top of whatever effect the MTHFR>CT has. rs819130 is a folate transporter, but in CCs, not efficient. As far as I can tell, no one quite has a handle on high homocysteine yet. I follow the research avidly hoping to find out as much as I can about my condition, so I can figure out how to moderate my epigenome to counteract the effects. I've seen what it did to my father, my uncle and my grandmother. I'm aware of what it did to my great-grandmother. None of them lived long enough to be affected by late onset Alzheimer's but high homocysteine is a risk factor. Alzheimer's is definitely a fate I wish to avoid. So far I think my best bet is strenuous daily exercise and reducing my calorie and sugar intake. I also have risk factors for diabetes, so I've been trying to eat like a diabetic as best I can. All the people in my family who share the high homocysteine trait are now deceased, so they won't be enrolling in PGP. My brother has a rare neurological disease. MSA (symptoms similar to ALS). He is enrolled in a trial through UCLA, but he's getting worse, and they think he's probably getting the placebo. His wife is planning to take hin to China for a stem cell transplant. However, I doubt that his issue is related to mine. I wouldn't dare ask him to enroll in PGP at this point.
Disease/trait: Onset Congenital / present at birth
Disease/trait: Rarity Fairly common
Disease/trait: Severity Moderate severity disease
Disease/trait: Relative enrollment No
Disease/trait: Diagnosis Yes
Disease/trait: Genetic confirmation Yes
Disease/trait: Documentation Yes
Disease/trait: Documentation description I have genetic tests from Berkeley Heart Lab and Health Diagnostic Laboratory that confirm MTFHR 677>CT. I have a subscription to 23and me that allows me to browse raw date, so I'm able to correlate my condition to the latest genetic research on high homocysteine. I was first tipped off to my condition after my father had a heart attack in Canada. His cardiologist told him he had the highest level of homocysteine that had ever been tested in the lab that covers all of Western Canada and that his condition was genetic and all his children should be test for it. None of my sisters have it. I'm not sure about my brother, but I don't think he does either. Classic one out of four.
Sex/Gender Female
Race/ethnicity White
Maternal grandmother: Country of origin United States
Paternal grandmother: Country of origin United States
Paternal grandfather: Country of origin United States
Maternal grandfather: Country of origin United States
Enrollment of relatives No
Enrollment of older individuals Yes
Enrollment of parents No
Have you uploaded genetic data to your PGP participant profile? Yes, I have uploaded genetic data
Have you used the PGP web interface to record a designated proxy? Yes
Have you uploaded health record data using our Google Health or Microsoft Healthvault interfaces? Yes
Uploaded health records: Update status Yes
Uploaded health records: Extensiveness 5
Blood sample Yes
Saliva sample Yes
Microbiome samples Yes
Tissue samples from surgery Yes
Tissue samples from autopsy Yes

Absolute Pitch Survey [see all responses]

Can tell if notes are in tune: Yes
Can sing a melody on key: No
Can recognize musical intervals: Not sure
Do you have absolute pitch? No

Enrollment History

Participant ID:hu6D1115
Account created:2009-05-21 22:19:27 UTC
Eligibility screening:2009-05-21 22:26:22 UTC (passed v1)
Exam:2009-05-21 23:53:08 UTC (passed v1)
Consent:2015-08-06 14:05:10 UTC (passed v20150505)
Enrolled:2010-10-10 16:22:46 UTC